Threshold Disease signifies stage of retinopathy of prematurity with ROP in Zone II stage 3 (less than 5 contiguous or 8 non contiguous clock hours) or Zone II stage 3 (5 contiguous or 8 non contiguous clock hours) without plus disease or Zone I, stage 3 with / without plus disease. Many doctors use this as the current criteria of initiating treatment.
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Retinopathy of Prematurity (ROP) Guide Retinopathy of Prematurity is a blinding eye disease of premature babies and very low birth weight infants
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